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    Victoria Toline would hunch over the kitchen table, steady her hands and draw a bead of liquid from a vial with a small dropper. It was a delicate operation that had become a daily routine — extracting ever tinier doses of the antidepressant she had taken for three years, on and off, and was desperately trying to quit.“Basically that’s all I have been doing — dealing with the dizziness, the confusion, the fatigue, all the symptoms of withdrawal,” said Ms. It took nine months to wean herself from the drug, Zoloft, by taking increasingly smaller doses.“I couldn’t finish my college degree,” she said. “Only now am I feeling well enough to try to re-enter society and go back to work.”Long-term use of antidepressants is surging in the United States, according to a new analysis of federal data by The New York Times. Some 15.5 million Americans have been taking the medications for at least five years. The rate has almost doubled since 2010, and more than tripled since 2000. Toline, have been on antidepressants for at least two years, a 60 percent increase since 2010. The drugs have helped millions of people ease depression and anxiety, and are widely regarded as milestones in psychiatric treatment. Many, perhaps most, people stop the medications without significant trouble. prednisone gout treatment Zoloft A lot of people these days are turning on to medicines for personal support. While this kind of approach is expensive and deemed dangerous when overdosed, it is undeniable that most of the medicines prescribed by the doctors and available over the counter really help lives get better. One of the most common and widely used medicines are Paxil and Zoloft. These medications fall under the selective serotonine reuptake inhibitor type or SSRI. However, they have different features and can treat different symptoms of depressions. Here are the differences of the features of the most highly competing anti-depressants drugs in the market. Paroxetine or otherwise known as Paxil can treat not only depression, but also disorders such as obsessive compulsive disorder, social anxiety disorder and panic disorder. Glaxo Smith Kline is the company that manufactured the drug Paxil.

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    Paxil, or paroxetene, is one of those medications—and it actually does double-duty, by treating both anxiety and depressive disorders. alone (12.7 percent of Americans take antidepressants, according to the Centers for Disease Control). But, while it can make living with anxiety or depression more manageable, the side effects of Paxil aren't necessarily harmless. Like Zoloft and Prozac, Paxil is “an SSRI, or selective serotonin reuptake inhibitor, which means it works on the serotonin system in your brain,” says Alison Hermann, M. D., a clinical psychiatrist at Weill Cornell Medicine and New York-Presbyterian Hospital. “Manipulating the levels of serotonin in your brain will work on a number of systems, including the ones that regulate mood and behavior, as well as arousal and sleep,” says Hermann. Since serotonin is the “feel-good” hormone, boosting those levels can make a major difference in the way you feel. SSRIs may reduce the frequency and severity of migraine headaches and are possibly effective in reducing the pain of diabetic neuropathy. Medical literature supports the use of SSRIs for the treatment of many conditions outside of the indications approved by the U. A side effect of SSRIs coincidentally provides therapy for premature ejaculation. PARMAN, LCDR, MC, USNR, Naval Hospital Jacksonville, Jacksonville, Florida Am Fam Physician. Related Editorial Selective serotonin reuptake inhibitors (SSRIs) are widely used because of their safety, tolerability, and demonstrated efficacy across a broad range of clinical conditions. SSRIs offer a reasonable alternative to traditional therapy for generalized anxiety disorder. When taken in combination with tricyclic antidepressants, SSRIs offer more potent therapy for fibromyalgia than either agent alone. SSRIs appear to be effective in some patients with neurocardiogenic syncope that is refractory to standard therapies. Clinical experience supported by ongoing research continues to expand on the broad array of therapeutic applications for this class of medication. Selective serotonin reuptake inhibitors (SSRIs) were initially developed to relieve depression and have become the most commonly prescribed class of antidepressants.1 SSRIs block the reuptake of serotonin at the presynaptic neuron, with minimal or no effect on norepinephrine or dopamine.

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