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In the first session, participants were given either doxycycline or a placebo and were taught to associate a certain color with an electric shock. A week later, the participants were shown the same colors accompanied with a loud sound, but no shock. The researchers measured the participants’ fear responses by tracking their eye blinks. The response was calculated by subtracting the baseline startle response from the response to the sound when the “bad” color was shown. Participants who had taken doxycycline experienced a fear response 60% lower than those who had a placebo. The results indicate that doxycycline can reduce fear memory response in individuals, which can play a potentially significant role in PTSD, which is characterized by overactive fear memory. 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