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In a population based study of drug induced liver. propranolol and diabetes Pharmacology & Drug Study Notes ciprofloxacin. Facebook;. Ciprofloxacin promotes breakage of double-stranded DNA in susceptible organisms and inhibits DNA gyrase. Ciprofloxacin extended-release long-acting tablets are used to treat kidney and urinary tract infections; however, some types of urinary tract infections should only be treated with ciprofloxacin extended release tablets if no other treatment options are available. Ciprofloxacin is in a class of antibiotics called fluoroquinolones. (FDA) for the treatment and prevention of several infections caused by designated, susceptible bacteria, for example, certain urinary tract infections, lower respiratory tract infections, and skin infections. Some bacterial infections are opportunistic infections (OIs) of HIV. An OI is an infection that occurs more frequently or is more severe in people with weakened immune systems—such as people with HIV—than in people with healthy immune systems. Off-label use, for example, can include using a drug for a different disease or medical condition. Good medical practice and the best interests of a patient sometimes require that a medicine be used off-label. The guidelines include recommendations on the following uses of ciprofloxacin: On-label uses: Take ciprofloxacin according to your health care provider’s instructions. Your health care provider will tell you how much ciprofloxacin to take and when to take it. Before you start ciprofloxacin and each time you get a refill, read any printed information that comes with your medicine. This includes bone and joint infections, intra abdominal infections, certain type of infectious diarrhea, respiratory tract infections, skin infections, typhoid fever, and urinary tract infections, among others. Ciprofloxacin is used to treat a wide variety of infections, including infections of bones and joints, endocarditis, gastroenteritis, malignant otitis externa, respiratory tract infections, cellulitis, urinary tract infections, prostatitis, anthrax, and chancroid. Ciprofloxacin only treats bacterial infections; it does not treat viral infections such as the common cold. For certain uses including acute sinusitis, lower respiratory tract infections and uncomplicated gonorrhea, ciprofloxacin is not considered a first-line agent. Ciprofloxacin occupies an important role in treatment guidelines issued by major medical societies for the treatment of serious infections, especially those likely to be caused by Gram-negative bacteria, including Pseudomonas aeruginosa. 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