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    This is not a list of all drugs or health problems that interact with Diflucan (fluconazole tablets). Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Diflucan (fluconazole tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Diflucan is an oral antifungal medication that is used to treat vaginal thrush. Fluconazole, which is the active ingredient in this medication, can help provide relief from the discomfort of a yeast infection in as little as 24 hours. It is easy to take, especially when compared to pessaries and only involves taking a single dose. Fluconazole has highly effective antifungal properties allowing it to treat vaginal thrush by killing the actual Candida fungus responsible for the symptoms. It's able to do this by preventing the fungus from producing ergosterol, which is vital in the formation of fungal cell walls. If a fungus can't multiply or maintain its cell walls it dies, resulting in the infection clearing up within a few hours. Diflucan is mostly recommended as a vaginal thrush treatment for women over the age of 18.

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