Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Cost hydroxychloroquine Chloroquine and doxycycline Hydroxychloroquine rheumatoid arthritis mechanism Uso del medicamento plaquenil Background. Afghanistan's national guidelines recommend chloroquine for the treatment of Plasmodium vivax infection, the parasite responsible for the majority of its malaria burden. Chloroquine resistance in P. vivax is emerging in Asia. Therapeutic responses across Afghanistan have not been evaluated in detail. Quick treatment of malaria infection is needed to prevent serious, possibly fatal, outcomes. When using chloroquine for treatment of malaria, tell your doctor if your condition persists or worsens. Treatment of P. vivax infections. P. vivax infections should be treated with an ACT or chloroquine in areas without chloroquine-resistant P. areas where chloroquine-resistant P. vivax has been identified, infections should be treated with an ACT, preferably one in which the partner medicine has a long half-life. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine treatment for vivax malaria Aralen chloroquine Malaria Drug Side Effects & Dosage, Chloroquine Oral Uses, Side Effects, Interactions, Pictures. Hydroxychloroquine treatment of rheumatoid arthritisPlaquenil not workingPlaquenil for sjogren's syndrome If species later identified as P. vivax or P. ovale, add primaquine or tafenoquine if not G6PD deficient by quantitative testing ‡Drug options for chloroquine-resistant P. falciparum may be used. Algorithm for Diagnosis and Treatment of Malaria * Algorithm for Diagnosis and Treatment of Malaria. WHO Overview of malaria treatment. Mefloquine Dosage Guide with Precautions -. Malaria. Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. ovale, and P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Sep 15, 2001 These studies suggest chloroquine resistance arose in ⩾4 distinct geographic foci and substantiate an important role of immunity in the outcomes of resistant infections after chloroquine treatment. P. vivax which also causes human malaria, appears to differ from P. falciparum in its mechanism of chloroquine resistance. Investigation of the. Persons acquiring P. vivax infections in Papua New Guinea or Indonesia should initially be treated with a regimen recommended for chloroquine-resistant P. vivax infections. The treatment regimens for chloroquine-resistant P. vivax infections are quinine sulfate plus doxycycline or tetracycline, or, atovaquone-proguanil, or artemether.