It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, this medicine is not used to treat severe or complicated malaria. Malaria treatment chloroquine how many daily Half life of chloroquine Aug 05, 2015 About a month ago, I finally decided to start taking the Plaquenil. I took 100 mg daily for a week since I'm highly sensitive to new medications, with the goal of reaching 400 mg daily after three weeks. One of my most bothersome symptoms is muscle weakness and fatigue, and the Plaquenil seemed to exacerbate it dramatically. May 04, 2015 Just got back from my neurologist and I am officially a "zebra" - my extreme and fast developing proximal muscle weakness myopathy is from doesn't mean I don't have any muscle weakness from the scleroderma, but the crazy, out-of-control weakness was from Plaquenil. Sep 13, 2019 Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine It is also used to treat acute and chronic rheumatoid arthritis. Hydroxychloroquine is used to treat discoid lupus erythematosus (DLE) or systemic lupus erythematosus (SLE or lupus). Plaquenil muscle weakness Plaquenil and muscle weakness - Sjogren's World, Confirmed Plaquenil Muscle Toxicity - Scleroderma - Inspire Maculopathy plaquenilChloroquine purposePlaquenil and excessive sweatingIs there withdrawal from plaquenil Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Your doctor may test your knee and ankle reflexes and check you for muscle weakness if you’re on. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil Side Effects Common, Severe, Long Term -. Drug-related Myopathies of Which the Clinician Should Be Aware. Hydroxychloroquine and colchicine neuromuscular toxicity is well documented. The largest literature review on colchicine myopathy was conducted by Wilbur and Makowsky in 2004 where a database search found 75 cases. Most patients presented with proximal muscle weakness. A wide range of treatment durations were noted from 4 days to 11 yrs with cumulative daily doses of 1.4 ± 0.96 mg. The. Can Plaquenil cause Muscle Weakness? Muscle Weakness is a known side effect of Plaquenil. Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. May 23, 2016 Other potential side effects include but are not limited to nausea, changes in mood, muscle weakness, skin pigmentation and anemia. While the drug may be used during pregnancy, the potential benefits and risks should be discussed with your doctor. In summary, if you have Sjögren’s, hydroxychloroquine may be an option to help your symptoms.