One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Lysosome fusion inhibitor chloroquine Plaquenil and coumadin interaction Chloroquine crystal structure Spectral Domain Optical Coherence Tomography SD OCT uses light to capture micrometer-resolution, three-dimensional images from within optical scattering media. Multifocal Electroretinopathy measures electrical responses of various cell types in the retina. it is the photoreceptors that are the targets of hydroxychloroquine toxicity. Our patient demonstrates the importance of using the new recommended screening tools for the detection of early hydroxychloroquine toxicity. 10-2 HVF, SD-OCT, autofluorescence, or mfERG might have detected the hydroxychloroquine retinal toxicity on the day of her presenting symptoms and possibly earlier, potentially limiting the amount of visual loss. Plaquenil Toxicity - Bulls Eye Maculopathy 878 views 70-year-old woman with systemic Lupus erythematosus and clotting problems. She was on the Plaquenil for about eight years and then off the Plaquenil for the last eight years because she developed macular toxicity. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Oct images of plaquenil toxicity How to Succeed in Plaquenil Screenings, Hydroxychloroquine Plaquenil Toxicity and. Hydroxychloroquine and charcot marie tooth diseasePlaquenil eye icd 10Plaquenil lupus hair loss Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy Retinal toxicity from chloroquine CQ and its analogue, hydroxychloroquine HCQ, has been recognized for many years. Chloroquine toxicity remains a problem in many parts of the world, but is seen less frequently in the United States where the drug largely has been. Recommendations on Screening for Chloroquine and.. Plaquenil Toxicity - Bulls Eye Maculopathy - Retina.. Pause the Plaquenil?. Click to email this to a friend Opens in new window Click to share on Twitter Opens in new window Click to share on Pocket Opens in new window Dosage levels that can cause toxicity 6.5 mg/kg Hydroxychloroquine Plaquenil19 3 mg/kg Chloroquine Arlen With Plaquenil Plaquenil is manufactured in only a 200 mg tablet The typical dosage is either 200 or 400 mg per day 200 mg daily puts anyone under 68 pounds at risk1 SD-OCT images demonstrated loss of photoreceptor inner segment/outer segment IS/OS junction and a downward “sink-hole” displacement of inner retinal structures in areas of hydroxychloroquine toxicity corresponding to HVF 10-2 defects and ophthalmoscopic clinical examination findings.