Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Can i take prednisone and hydroxychloroquine together Can hydroxychloroquine cause dry eyes If the patient manifests the toxicity symptoms of Plaquenil, the standard of care is to stop taking the medication and to change the medication the patient is taking. Possible coordination with the dermatologist or the rheumatologist may be required for the continuous care. What are the signs and symptoms of Plaquenil damage? Plaquenil side effects start off by effecting the surface of the eye the cornea leading to verticillata. Verticillata are deposits of salts within the corneal epithelium. This does not cause any symptoms to the patient and is reversible when the medication is stopped. Plaquenil related eye complications are not common. Plaquenil can produce pigment changes in the macula of the retina. The retina is the part of the back of the eye that you see with. The macula is the central part of the retina responsible for central fine vision. With Plaquenil related toxicity, the pigment in the macula can change and alter vision by producing blurring and distortion of objects. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. What are symptoms of plaquenil eye problems Has anyone experienced plaquenil toxicity with damage to eyes?, Plaquinel Related Eye Problems - Fraser Eye Care Center Doses of plaquenilChloroquine phosphate nano reefHydroxychloroquine copay assistance programWhat is plaquenil used for in lymeDoes hydroxychloroquine lower blood sugar One of the most significant side effects of the drug is its possibility of causing eye problems resulting in blurred or decreased vision. The most common issue is damage to the retina. It can impair your color vision or damage the retinal cells particularly in the area right around the central vision. What can Hydroxychloroquine Plaquenil do to my eyes?. Conditions Plaquenil-related Eye Problems Eugene Eye Care. Plaquenil eye problems Mayo Clinic Connect. Dr. Fung’s case involved a 48-year-old woman with lupus. Nine years after discontinuing medical therapy, the patient had new scotomas, difficulty reading and progression of bull’s-eye maculopathy. Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. Common side effects Nausea and diarrhea This can often can be combatted by taking Plaquenil with food or milk. Dizziness Precautions with this side effect Do not drive, use machinery. Cramps. Headache. Dry skin. Loss of appetite.