I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Is hydroxychloroquine sulfate an immune suppressing drug Quinacrine chloroquine antimalarial Is chloroquine safe in first trimester of pregnancy I’ve been on plaquenil for over 20 years and just stopped taking it. I don’t think it has ever helped. I have tested negative on my ANA tests for the last 3 Year’s. Weird because I still have all the pain, plus terrible neuropathy due to autoimmune issues. Aug 26, 2016 Plaquenil is supposed to stay in your system for 1-2 months after you stop taking it. Try to rest, stay hydrated and away from sick ppl for now and hopefully you will not have any issues ranin02 Feb. 5, 2008 -- Heart attack survivors and other heart patients may be more likely to die or suffer a heart attack in the first three months after stopping the drug Plavix, new research shows. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Can plaquenil ever be stopped abruptly Discontinued Plaquenil.itching skin?, Stopping Plaquenil - General Discussion - Life With Lupus Hydroxychloroquine 200 mg discountsChloroquine molecular weightPlaquenil cost increaseCan plaquenil worsen neuropathyCat's claw and hydroxychloroquine Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. Protecting your eyesight when taking Plaquenil Lupus.. Study Stopping Plavix May Be Risky - WebMD. Taking Plaquenil for Rheumatoid Arthritis. Nov 12, 2009 Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. I can't believe you were told to stop taking plaquenil after only 6 months since it can take up to one YEAR to achieve full benefits! I don't know much about any sort of withdrawal but if I were you I'd start taking it again. I'd also have your thyroid checked. I'm hypothyroid and take levo along with he plaquenil. I took plaquenil on and off over a period of yrs. Stopped talikg fist time because it reacts with the sun. Got over heated one day and head felt like it was on fire. It was also causing hair loss. My doctor took me off it at the time. Because of A problem I have taking arthritis meds he suggested I try it again.