Synthesis of chloroquine from 4 7-dichloroquinoline

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  1. s!ntec Moderator

    Synthesis of chloroquine from 4 7-dichloroquinoline

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    Also known as 4,7-Dichloroquinoline. C9H5Cl2N, 198.05 ORDER NOW or ENQUIRE about Chloroquine related compound A. Comes with CoA, 1H-NMR, Mass, HPLC and MSDS. IR, 13C, 2D-NMRs, TGA, Structure Elucidation etc. also provided on request. Available in packs as per your requirement! Find out price, stock, Lead Time & shipping. Assured by strong scientific team. The application of ultrasound in the synthesis of com-pounds 2 and 3 is fulfilling some of the goals of “green and sustainable chemistry” as it has some advan-tages comparing with the traditional thermal methods in terms of reaction times, yields and purity of the products 16, 17. The reaction of 4,7-dichloroquinoline and o-phe- Dichloroquinoline - cas 86-98-6, synthesis, structure, density, melting point, boiling point

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    Synthesis of chloroquine from 4 7-dichloroquinoline

    Synthesis, antimalarial-, and antibacterial activity., Click synthesis of new 7-chloroquinoline derivatives by using.

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  4. Predicted data is generated using the US Environmental Protection Agency’s EPISuite™. Log Octanol-Water Partition Coef SRC Log Kow KOWWIN v1.67 estimate = 3.43 Log Kow Exper. database match = 3.57 Exper.

    • Dichloroquinoline C9H5Cl2N ChemSpider.
    • Dichloroquinoline - 86-98-6, C9H5Cl2N, density, melting..
    • A New Synthesis of Chloroquine - Journal of the American Chemical..

    Chloroquine is a member of the drug class 4-aminoquinoline. It works against the asexual form of malaria inside the red blood cell. Chloroquine was discovered in 1934 by Hans Andersag. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. Chloroquine and its metabolites were prepared from 7‐chloro‐1,2,3,4‐tetrahydroquinolin‐4‐one through an aryl substitution with the corresponding amines; and the amodiaquine and its metabolites were prepared from 4,7‐dichloroquinoline in a similar fashion. Application 4,7-Dichloroquinoline is used in the synthesis of hybrid aminoquinoline-triazine derivatives that show anti-microbial activity. In addition, it is used in the synthesis of novel oxazolidinones as anti-microbial agents showing efficacy against common bacterial strains.

  5. iggy2007 Well-Known Member

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  6. SLIM9093 Well-Known Member

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