Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Long-term progression of hydroxychloroquine retinopathy off the drug Plaquenil mixed with alcohol Side effects of hydroxychloroquin Plaquenil to treat lupus The Plaquenil is supposed to kick in in 3 to 6 months. I think it was 8 months for me. One day I was congratulating myself for getting so many things done and I realised that the days had been getting better without my noticing. In the beginning I also was on a low dose of prednisone, which helped until plaquenil kicked in. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Hydroxychloroquine oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. The avgerage dosage a person takes of plaquenil Protecting your eyesight when taking Plaquenil Lupus., Plaquenil Hydroxychloroquine - Side Effects, Dosage. Hydroxychloroquine reviews eyesHydroxychloroquine pregnancy category I usually start with a low dose of 100-200 mg per day to help the patient adapt to the medicine and allow an increase in dose later to as high as 300-400 mg per day. Less common adverse effects of Plaquenil are drug-induced skin rashes. These rashes may consist of many small red bumps or bright red skin covering most of the body. Plaquenil Use in Autoimmune Diseases. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Who Is at Risk for Vision Loss with Plaquenil? - American.. Initial dose for the treatment of SLE, 400mg×2/day, is about the dose used in one of the studies above. Maintenance dose would keep the serum concentration constant. Assuming HCQ is effective, it would most definitely be protective in doses used in SLE patients. Medscape - Indication-specific dosing for Plaquenil hydroxychloroquine sulfate, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Download PDF. Drug-induced ocular side effects are back in the spotlight, thanks to the Academy’s revision of its recommendations on screening for retinal toxicity from chloroquine and its analogue hydroxychloroquine Plaquenil. 1 There are hundreds of drugs with potential retinal toxicity—so many that the National Registry of Drug-Induced Ocular Side Effects doesn’t stratify them by.