And is one of several anti-malarial medications recommended by the United States Centers for Disease Control and Prevention for this purpose. It is also recommended by the Infectious Disease Society of America for malaria prophylaxis as a first or second-line agent, depending on resistance patterns in the malaria found in the geographic region visited. What are the side affects of hydroxychloroquine Took plaquenil during pregnancy Plaquenil causing muscle weakness Aralen phosphate side effects Chloramphenicol is an inhibitor of this enzyme and may decrease the clearance of mefloquine and increase mefloquine systemic exposure. Chloroquine Major Due to the potential for QT prolongation and torsade de pointes TdP, caution is advised when administering chloroquine with mefloquine. In addition, concurrent use may result in seizures. Mefloquine Hydrochloride Tablets USP are indicated for the treatment of mild to moderate acute malaria caused by mefloquine-susceptible strains of Plasmodium falciparum both chloroquine-susceptible and resistant strains or by Plasmodium vivax. Treatment of Acute Malaria Infections Mefloquine hydrochloride tablets are indicated for the treatment of mild to moderate acute malaria caused by Mefloquine-susceptible strains of P. falciparum both chloroquine-susceptible and resistant strains or by Plasmodium vivax. There are insufficient clinical data to document the effect of Mefloquine in malaria caused by P. ovale or P. malariae. Mefloquine does not eliminate parasites in the liver phase of the disease, and people with P. Mefloquine is used as a treatment for chloroquine-sensitive or resistant Plasmodium falciparum malaria, and is deemed a reasonable alternative for uncomplicated chloroquine-resistant Plasmodium vivax malaria. Mefloquine hydrochloride chloroquine Mefloquine Professional Patient Advice -, Mefloquine C17H16F6N2O - PubChem Plaquenil and hair loss site sjogrensworld.orgDoes hydroxychloroquine cause weight gain Mefloquine Hydrochloride Tablets USP are an antimalarial agent available as 250 mg tablets of mefloquine hydrochloride equivalent to 228 mg of the free base for oral administration. Mefloquine Hydrochloride USP is a 4-quinolinemethanol derivative with the specific chemical name Mefloquine Hydrochloride Tablets USP. Mefloquine - FDA prescribing information, side effects and.. Mefloquine HCL - WebMD. Mefloquine Hydrochloride Oral tablet drug summary. Find medication information including related drug classes, side effects, patient statistics and answers to frequently asked questions. Visit for more details. Mefloquine is a quinolinemethanol derivative with antimalarial, anti-inflammatory, and potential chemosensitization and radiosensitization activities. Although the exact mechanism remains to be elucidated, mefloquine, a weak base, preferentially accumulates in lysosomes and disrupts lysosomal function and integrity, thereby leading to host cell death. Lariam mefloquine is indicated for the treatment of mild to moderate acute malaria caused by mefloquine-susceptible strains of P. falciparum both chloroquine-susceptible and resistant strains or by Plasmodium vivax.