Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil make me itch Pain medication plaquenil Feb 09, 2018 In this video, I will explain into one of the main antimalarial drug, chloroquine. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive. Mechanism of Action Chloroquine is an antimalarial agent. While the drug can inhibit certain enzymes, its effect is believed to result, at least in part from its interaction with DNA. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Chloroquine is also used to treat amebiasis (infection caused by amoebae). Chloroquine is used to treat and to prevent malaria. What is the mode of action of chloroquine Chloroquine Indications, Side Effects, Warnings -, CHLOROQUINE PHOSPHATE TABLETS, USP 250 MG and 500 MG Synthesis of chloroquine from m-chloroanilineOphthalmology guidelines for plaquenil Chloroquine resistance is associated with a decrease in the amount of chloroquine that accumulates in the food vacuole, the site of action for chloroquine. The mechanism for this decreased accumulation is controversial. Some studies have shown that the decrease in drug accumulation is due to an increase in drug efflux. Mechanisms of drug action and resistance. Hydroxychloroquine - Wikipedia. Chloroquine Uses, Side Effects & Warnings -. Chloroquine works to treat malaria by killing the Plasmodium parasites that cause the infection. This eMedTV segment describes chloroquine's mode of action and provides a link to more detailed information on this medication. Antimalarial mode of action and resistance. Chloroquine acts exclusively in the erythrocyte stage of malaria parasites. The antimalarial mechanism of action from chloroquine has not been fully elucidated. Many theories have been developed to elucidate the chloroquine mechanism of action, including DNA binding and inhibition of various enzymes and/or transporters. In this video, I will explain into one of the main antimalarial drug, chloroquine. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive.