Because lupus is an autoimmune disease that affects the collagen tissue in the entire body, the collagen component of the mucosa of the mouth, including the gingival tissue and salivary glands also present the symptoms seen elsewhere in the body. A person with lupus demonstrates increased levels of xerosthemia or dry mouth leading to increased levels of caries, periodontitis and candidiasis. Metoprolol and plaquenil Does hydroxychloroquine cause health problems Hydroxychloroquine dose for malaria Plaquenil retinal screening guidelines afters stopping Here is more than you ever wanted to know, I am sure, about drug induced hyperplasia. In this case, "gingival hyperplasia". Just fancy words, gingival means gums, and hyperplasia means cells growing too fast, too many of them and they accumulate over time. Yesterday there was a post on ACOR about a patient with gingival overgrowth. Jul 15, 2010 Gingival hyperplasia, with its potential cosmetic implication and tendency to provide niche for further growth of microorganism, possess a serious concern to patients and clinicians. Calcium channel blockers are considered as potential etiological agent for inducing gingival enlargement. The risk of gingival hyperplasia may be lessened with meticulous oral hygiene. Other side effects include hirsutism, tremor, paraesthesia and headache. 17 Monitoring recommendations Baseline CBC, creatinine on two different occasions, uric acid, LFTs and blood pressure on two different occasions. What are called leukoplakic lesions (white scaly tissue detaching from the underlying tissue) can appear on the skin or mucosa of the cheek, palate, o r vermillion border of the lips. The gingival tissue may become red and appear to be desquamating. Hydroxychloroquine gingival hyperplasia Gingival Hyperplasia Clinician's Brief, Management of amlodipine-induced gingival enlargement Series. Oct and plaquenil toxicityHydroxychloroquine nsaidPlaquenil scalp dandruff Gingival hyperplasia from phenytoin. The mechanisms of adverse reactions to drugs vary. Some, like the urticarial or eczematous, are clearly based on an allergic or immunologic mechanism; others are utterly obscure in mechanism. Such is the gingival hyperplasia caused by phenytoin. Picture of Gingival Hyperplasia from Phenytoin. Disease-modifying Anti-rheumatic Drugs DMARDs for.. Gingival Hyperplasia - Treatment, Symptoms, Causes, Pictures. Hydroxychloroquine may be adequate in conjunction with steroids but often immunosuppression is required. Azathioprine has been used most widely but in recent years methotrexate has been used increasingly as has mycophenolate. Cyclosporin can also be useful, particularly in the treatment of thrombocytopenia. Gingival hyperplasia is an enlargement or overgrowth of the gum tissue, also known as the gingiva, around the necks of the teeth. It is an increase in the size of the gingival tissues and thus the term overgrowth is many times used in place of the term hyperplasia. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis.