But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. Read more Anxiety over potential eye problems with Hydroxychloroquine is completely unwarranted if the dose is kept below 6mg/kg (2.2lbs) of body weight. Read more See 1 more doctor answer It can cause eye problems so you need to see an ophthalmologist and peridoic screenings. Read more Results are very good, particulary when used alone and better with methotrexate. Hydroxychloroquine insomnia Plaquenil retinopathy screening Mar 05, 2010 provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Doctors give trusted answers on uses, effects, side-effects, and cautions Dr. Namey on plaquenil substitute Plaquenil is also known as hydroxychloroquine, so the parent drug Chloroquine can be substituted. But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Plaquenil ® hydroxychloroquine sulfate can potentially interact with a few other medications. Some of these medicines that may lead to Plaquenil drug interactions include Certain beta blockers, such as Bisoprolol Zebeta ® Metoprolol Lopressor ®, Toprol XL ® Propranolol Inderal ® Sotalol Betapace ® Timolol Blocadren ® Chloroquine can be substituted for Plaquenil but only in limited circumstances. Please provide more detailed information if you want a more specific answer. Read more See 1 more doctor answer Depends on what you are being treated for.... Read more While plaquenyl is a slow acting but effective drug, Prednisone is used in much higher doses in active sle. Arthritis (non-deforming) or arthralgias associated with the disease will have substantial pain relief with a dose this low. It's infusion intervals are longer, because the turnover of recptors is slower than the production of tnf-a itself. So other meds like Imuran and Cell Cept (mycophenolate mofetil) also reduce flares, but also increases infection. Read more It depends why you are taking Plaquenil in the first place. Apart from some stomach quiziies, I have never stopped this drug, as long as it demonstrated it is working. Other than that we see a few people who have increased skin pigmentation called "plaquenil ochronosis". The dirrence with Remicade (infliximab) is that it blocks the tnf-a receptor, rather than binding tnf-a itself, but it accomplishes the same thing. Is there a natural drug substitute for plaquenil Alternatives to plaquenil Anti-Inflammatories discussions., Plaquenil substitute - Things You Didn’t Know What is side effects of plaquenilCost plaquenil thru prime therapeuticsPlaquenil not working what next Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Plaquenil Interactions - Antibiotics Home Page. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil is also known as hydroxychloroquine, so the parent drug Chloroquine can be substituted. But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. Drug interactions are reported among people who take Turmeric and Plaquenil together. This study is created by eHealthMe based on reports of 97 people who take Turmeric and Plaquenil from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can manage your drugs like 5 million people do in Medicare, and even better. May 20, 2008 Because the action of Plaq isn't really understood in SjS, and it's a unique classification of drug in treating AIs, there really isn't a substitute for it, but there are other classes of drugs, also called DMARDS disease modifying anti-rheumatic drugs that are also used.