Always check with your healthcare provider before taking any medications, vitamins, or supplements; before beginning exercise programs, or making changes in your health care practices. Plaquenil is the brand name for the prescription drug hydroxychloroquine. Plaquenil and knee replacement Stopping plaquenil for surgery Prilosec and plaquenil interactions How to start plaquenil Sexual activity may be more comfortable with the use of a water-based lubricant. In women who are postmenopausal, dryness may be due to vaginal atrophy in addition to—or instead of—Sjogren’s syndrome. Prescription estrogen, in the form of a tablet, cream, or ring that you can insert into the vagina, may make you more comfortable. Jun 11, 2013 For many patients with Sjogren's, Plaquenil hydroxychloroquine has long been the go to drug that their doctors prescribe. It is often the first line of attack before other more aggressive therapies are added such as methotrexate or rituximab that have bigger impacts on the immune system. It's also common for relatives of people with Sjögren’s syndrome to develop other types of autoimmune disease such as lupus or hypothyroidism. While there isn’t yet a concrete answer as to why Sjögren’s syndrome affects women more often than men, researchers believe the hormone estrogen might play a role. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Plaquenil use for sjogrens syndrome Hydroxychloroquine Plaquenil, Study Raises Questions about Sjogren's and Plaquenil Drug interaction of allopurinol and plaquenilChloroquine mice scratchingChloroquine in amoebiasis Hydroxychloroquine Plaquenil, a drug designed to treat malaria, is often helpful in treating Sjogren's syndrome. Drugs that suppress the immune system, such as methotrexate Trexall, also might be prescribed. Sjogren's syndrome - Diagnosis and treatment - Mayo Clinic. Sjögrens Syndrome - Arthritis Foundation. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Sjögren syndrome SjS, SS is a long-term autoimmune disease that affects the body's moisture-producing glands. Primary symptoms are a dry mouth and dry eyes. Other symptoms can include dry skin, vaginal dryness, a chronic cough, numbness in the arms and legs, feeling tired, muscle and joint pains, and thyroid problems. User Reviews for Plaquenil to treat Sjogren's Syndrome. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. What is Plaquenil and what are its benefits for Sjögren’s patients? Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s.