Too much calcium in your blood can weaken your bones, create kidney stones, and interfere with how your heart and brain work. Hypercalcemia is usually a result of overactive parathyroid glands. Plaquenil and orthopedic surgery Hydroxychloroquine blood tests Apr 17, 2017 Once the sodium level drops, our cells expand from the abundance of water present in the blood. This can cause mild symptoms of nausea and headaches and eventually lead to rapid brain swelling and death. A normal sodium level is between 135 to 145 milliequivalents per liter mEq/L. Hyponatremia is present when levels drop below 135 mEq/L. If levels of calcium are low for long periods, people may develop dry scaly skin, brittle nails, and coarse hair. Muscle cramps involving the back and legs are common. Over time, hypocalcemia can affect the brain and cause neurologic or psychologic symptoms, such as confusion, memory loss, delirium, depression, and hallucinations. Hi there, I have low calcium levels as well as low vit D. They reckon it's the mtx that did it to me, even though I was eating well! I take supplements now and I'm suppose to go for a bone density scan since I've been on the supplements for over 3 months, but like most of us on this site, I've put off the scans because I've had so many medical tests for RA related issues I can't face another. Other causes of hypercalcemia include cancer, certain other medical disorders, some medications, and taking too much of calcium and vitamin D supplements. These four tiny glands are situated behind the thyroid gland. Plaquenil causes lowcalcium levels Hydroxychloroquine-Induced Retinal Toxicity - American., Hypocalcemia Low Level of Calcium in the Blood. Mixed connective tissue disease hydroxychloroquine Idaho Nephrology Associates provides care to adult patients suffering from kidney-related diseases and disorders including high blood pressure, hypertension, diabetes, chronic kidney disease, glomerulonephritis, end stage renal disease, post-operative transplant management, disorders of electrolyte and mineral metabolism, and kidney stones in Boise, Idaho and the surrounding Calcium and Chronic Kidney Disease - Idaho Nephrology.. Hypocalcemia? -. Long-Term Side Effects of Plaquenil for Rheumatoid.. Hydroxychloroquine and diabetes drugs all decrease your blood sugar level. Taking hydroxychloroquine with these drugs could cause hypoglycemia low blood sugar. These Drugs Can Mess With Your Potassium Levels Sharon Orrange, MD, MPH Dr. Orrange is an Associate Professor of Clinical Medicine in the Division of Geriatric, Hospitalist and General Internal Medicine at the Keck School of Medicine of USC. People who have a condition that causes them to spend a lot of time sitting or lying down can develop hypercalcemia. Over time, bones that don't bear weight release calcium into the blood. Severe dehydration. A common cause of mild or transient hypercalcemia is dehydration. Having less fluid in your blood causes a rise in calcium concentrations.