Personally, I will be taking this when Casodex begins to fail. Bicalutamide and Chloroquine study"Taken together, our data suggest that autophagy is a protective mechanism against androgen deprivation in HRPCa cells and that chloroquine could restore hormone dependence. I also note this: "The strategy is currently being tested in clinical trials, and preliminary results are promising. Plaquenil toxicity oct findings Hydroxychloroquine sulphate bp 200mg Prostate cancer cells could be sensitized to different apoptotic stimuli by inhibiting autophagy, which happens during ADT. In fact, appropriate stimuli can lead prostate cancer cells to apoptosis, even though these cells tend to evolve into an androgen-resistant phenotype. To this regard, a recent investigation by Saleem et al. Summary. Chloroquine is an anti-malarial drug available at pharmacies for people traveling to area with malaria risks. Note based on a RGCC chemosensitivity analysis I have seen at a German clinic, Hydroxychloroquine has been effective in killing the cancer cells of 5 out 7 patients that were tested. The anti-cancer effect of the antimalarial agent chloroquine when combined with conventional chemotherapy has been well documented. To date, it was assumed that chloroquine increases the. The plant contains a volatile oil with a high level of thujone (see Thuja). This set of data could lead to the development of new therapeutic strategy against HRPCa."Comments and discussion would be much appreciated... The catch, though, is that it's not always possible to give patients a high enough dose of hydroxychloroquine to have an effect on their tumor cells." "Available scientific evidence does not support claims that wormwood is effective in treating cancer, the side effects of cancer treatment, or any other conditions. Chloroquine and prostate cancer Antimalarial drugs could support existing cancer., Chloroquine & Hydroxychloroquine supporting chemo. Chloroquine side effects treatmentCommon side effects of plaquenil Nov 24, 2017 2017, November 24. Antimalarial drugs could support existing cancer treatments in two-pronged attack Chloroquine and hydroxychloroquine could make cancer treatments more effective. ScienceDaily. Antimalarial drugs could support existing cancer treatments.. Malaria medicine chloroquine inhibits tumor growth.. Hydroxychloroquine in Treating Patients With Rising PSA.. Herbal and Medicinal Plants Molecules Towards Treatment of Cancer A Mini Review, Lakshmi Priya. M. Bhanu Priya. K, Venkata Subbaiah Kotakadi* Josthna. P Prostate cancer is one of the most common malignancies. Increasing evidence suggested that endothelial cells may contribute to prostate cancer progression and metastasis. Most recently, autophagy has been proposed to plays a significant role in tumorigenesis and metastasis. Also, it is reported that downregulation of androgen receptor AR induces autophagy in prostate cancer cells. However. In the last two decades, accumulating evidence pointed to the importance of autophagy in various human diseases. As an essential evolutionary catabolic process of cytoplasmatic component digestion, it is generally believed that modulating autophagic activity, through targeting specific regulatory actors in the core autophagy machinery, may impact disease processes. Both autophagy upregulation.