Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil sulfate uses Chloroquine and proguanil pregnancy Plaquenil retinal toxicity symptoms As PLAQUENIL may enhance the effects of a hypoglycemic treatment, a decrease in doses of insulin or antidiabetic drugs may be required. Also, there may be an increased risk of inducing ventricular arrhythmias if PLAQUENIL is used concomitantly with other arrhythmogenic drugs. Drug Revised guidelines recommend19 • Baseline examination within first year of usage of Plaquenil Hydrochloroquine or Aralen Chloroquine • Annual screening after 5 years of use **Interesting, The Royal College of Ophthalmologists in Great Britain does NOT recommend routine screening for toxicity with antimalarial drug use Hydroxychloroquine Plaquenil™ What is hydroxychloroquine? Hydroxychloroquine also known as hydroxychloroquine sulfate is an arthritis medicine. that also can be used to prevent malaria. It is available in the United States by prescription only. It is sold under the brand name Plaquenil and it is also sold as a generic medicine. It is available in Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Is plaquenil an antimalarial drug Why are treatments that were developed for malaria now used., Early Plaquenil Toxicity Detected without Bull’s Eye Maculopathy Lysosomal acidification chloroquineChloroquine-like drugsPlaquenil causing muscle weaknessPlaquenil drug name Drug structure and chemistry. Commonly used antimalarial drugs can be divided into different classes on the basis of their core structure. Hydroxychloroquine and chloroquine belong to a class of. Mechanisms of action of hydroxychloroquine and chloroquine.. Medicines for the Prevention of Malaria While Traveling.. Antimalarials for Rheumatic Conditions - Quinacrine, Chloroquine. Antimalarial drugs. Hydroxychloroquine is used to treat malaria, and researchers have found that this drug also helps with lupus flares. These drugs work well with mild to moderate cases of lupus. Hydroxychloroquine is in the antimalarial and 4-aminoquinoline families of medication. Hydroxychloroquine was approved for medical use in the United States in 1955. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. Hydroxychloroquine is an antimalarial drug used to prevent and treat malaria. Hydroxychloroquine Plaquenil is also a disease-modifying anti-rheumatic drug DMARD used to treat both acute and chronic rheumatoid arthritis, systemic lupus erythematosus, and discoid lupus erythematosus.