One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil constipation Hydroxychloroquine plaquenil tablet 200 mg dose 200 mg freq bid This means many people taking Plaquenil for RA are taking a dose of 400mg a day or higher. Pigment deposits in the retina can cause vision changes, according to Steven Ofner, M. D. of Eugene Oregon Eye Care. Signs of retinal damage include blurry or distorted vision, flashes of light or floaters, or loss of night vision. Do any of you have any tips that you use to help with light sensitivity, if you have eye floaters, and if you use a computer a lot? I know about the "blink, blink, blink" part when looking at a computer screen - I do that, it's just hard to focus to see. I make sure and put in eye drops prior to working on the computer. The Link between Eye Problems and Lupus Medications. Many eye problems in patients with lupus originate from the drugs doctors use to treat lupus itself. Three groups of medications prescribed for lupus patients are immunosuppressive drugs such as methotrexate and mycophenolate, antimalarials such as hydroxychloroquine Plaquenil®, and. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil and eye floaters Conditions Plaquenil-related Eye Problems Eugene Eye Care, Eye Floaters, Light Sensitivity & Computer's Chloroquine synthesis slideshareIs hydroxychloroquine an immune modulatorPlaquenil testing Annual comprehensive eye examinations are recommended by the American Optometric Association for people with lupus, especially for anyone taking Plaquenil. As a precaution, people treated with Plaquenil should get a baseline eye exam before or soon after starting the drug and visit an eye doctor ophthalmologist annually. How lupus affects the eyes Lupus Foundation of America. What Eye Problems and Conditions Are Associated With Lupus?. Healthboards - Immune & Autoimmune - Lupus eye floaters. Hydroxychloroquine Plaquenil Plaquenil is used for the treatment of systemic lupus erythematosus, rheumatoid arthritis, and other inflammatory and dermatologic conditions. Retinal toxicity from Plaquenil is a serious concern and sometimes there is a progression of visual loss over several years after the drug has been stopped. Beyond Plaquenil Other Drugs, Other Problems. If you’re looking for a comprehensive assessment of drug reactions that relate to the eye, Dr. Fraunfelder and his father, Frederick T. “Fritz” Fraunfelder, MD, along with Wiley A. Chambers, MD, literally wrote the book. 3 “So many drugs can cause ocular side effects that if you’re trying to make a point about which drugs to watch out. I have recently been diagnosed with Plaquenil Toxicity and told there is no reversal of symptoms or cure. I have had a vision disturbance that has gotten increasingly worse over the last 13 years. I was on Plaquenll for 27 yrs & had my eyes checked faithfully every year.