When taken at high doses and for long durations, hydroxychloroquine has been known to cause parafoveal retinal toxicity. This toxicity is often insidious, causing serious, irreversible visual deterioration if not detected early. How does chloroquine phosphate work Plaquenil make you gain weight Fundus Autofluorescence Is Not the Best Early Screen for Hydroxychloroquine Toxicity—Reply Ian R. Gorovoy, MD; Mark S. Gorovoy, MD Fundus autofluorescence images of the left eye of a 59-year-old women with sarcoidosis who received 200 mg of hydroxychloroquine sulfate twice daily for 15 years. In early toxicity, 75 % developed progression after drug cessation, including disruption of the parafoveal EZ and retinal pigment epithelium and thinning of the ONL. Eyes with obvious toxicity had greater inferior outer ring thinning 12 months after drug cessation compared to early toxicity p = 0.002, 95 % CI −2 to −8 μm. Plaquenil Toxicity both Eyes - Partial Bull's Eye - Discontinued 6 Years ago Fundus Autofluorescence 1094 views 82-year-old woman was on Plaquenil from 1976 from 2005, 200 mg a day. It was discontinued because of abnormal visual fields 6 years ago. OD 20/32, OS 20/40 0 votes • No single imaging platform can confirm the presence of hydroxychloroquine toxicity, but a combination of imaging tests can provide ample evidence for diagnosis. • Long-term use of hydroxychloroquine sulfate may result in parafoveal retinal toxicity. Images early plaquenil toxicity fundus autofluorescence Hydroxychloroquine retinopathy A review of imaging, Expanded spectral domain-OCT findings in the early detection. Plaquenil retinopathy info for patient rheumatolAralen vs plaquenilPlaquenil avoidVision loss from plaquenilDiscontinuing plaquenil Our patient demonstrates the importance of using the new recommended screening tools for the detection of early hydroxychloroquine toxicity. 10-2 HVF, SD-OCT, autofluorescence, or mfERG might have detected the hydroxychloroquine retinal toxicity on the day of her presenting symptoms and possibly earlier, potentially limiting the amount of. Hydroxychloroquine Plaquenil Toxicity and Recommendations for Screening. Plaquenil Toxicity - Mild - Partial Bull's Eye Maculopathy - Retina.. The Nuts and Bolts of Fundus Autofluorescence Imaging.. Fundus Autofluorescence Is Not the Best Early Screen for Hydroxychloroquine Toxicity—Reply. These images were intended to remind ophthalmologists that. Early Plaquenil Toxicity. Photos courtesy of Dr. Jane Ann Grogg and Dr. Anna Bedwell, Indiana University School of Optometry. • Fundus Autofluorescence FAF Hydroxychloroquine Maculopathy An Update on Screening and Diagnosis A brief guide for imaging SHIRI SHULMAN, MD. H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus.