Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil for diarrhea Retinal toxicity from chloroquine apre-19 cells What eye exam is needed for plaquenil Jul 16, 2018 I have had this happen with other meds in the past and so eventually I realized it might be a reaction to the plaquenil. So I went off of it. Everything cleared up and I went back to normal. However, then my fatigue returned. After several months off of plaquenil, I went back on it, deciding to stick with the 100 mg per day. I am 99% sure that the Plaquenil has not caused your fatigue. If anything, it’s Lupus OR psychosomatic. Plaquenil is a slow-acting drug which is why you take it long term. It honestly takes on average 1 to 3 months to work and be built up in your system, which is why you typically have a 3-6 month review after being prescribed it. Chronic fatigue is a common RA symptom. Discover six ways you can better manage fatigue and find more energy to deal with rheumatoid arthritis. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Can plaquenil cause extreme fatigue Sjögrens Fatigue – an Autoimmune Conundrum! SjögrensLife, Extreme fatigue on Plaquenil? lupus Chloroquine for transductionPlaquenil treatmentDiagnosis code for plaquenil therapy Fatigue is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Pain. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is. Will you have Fatigue with Plaquenil - eHealthMe. Chronic Fatigue From RA 6 Ways to Fight Back Everyday Health. Stopping plaquenil. DailyStrength. Apr 28, 2009 And, as far as Plaquenil and eye problems, the Ophthamologists I've talked to including a Neuro Ophthalmologist say that while Plaquenil can cause serious damage to the optic nerve, it's very rare. Annual appointments with an ophthalmologist are important in order to catch any problems early. My rheumatologist just started me on plaquenil a couple of weeks ago. She said a half-dose - 200 mg because I'm skinny. My fatigue is out of control and ruining my life. I can barely hold on to my job and right after work, I fall asleep, like at 6 PM, then struggle with insomnia all night. Always feel exhausted. I appreciate all the comments and advice. I am going to talk with my RA doc about the cough at my next visit in early August. I see in the side-effect list that Plaquenil can cause the Bronchospasm, but it appears to be a very rare side effect.