Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Drug interaction between plaquenil and simvastitin Plaquenil dosage for sjogren& 39 Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. I have been on the plaquenil 200 mgm for about 4 months now. I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Noticed nothing different. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Side effects of stopping plaquenil Taking Plaquenil for Rheumatoid Arthritis, Let me tell you what weaning down from Plaquenil is like. Common side effects of plaquenilPlaquenil maculopathy fundus autofluorescencePlaquenil for lupus itp Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. A Disorder Of The Retina Of The Eye;. RARE side effects. Common and Rare Side Effects for Plaquenil Oral. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Plaquenil Side Effects on Your Eyes and Vision. Feb 19, 2020 SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Plaquenil side effects. Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Withdrawal syndrome is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Lyrica, and have Fibromyalgia. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly.