These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Malaria drug hydroxychloroquine What is the drug plaquenil used to treat In this review, we analyze Plaquenil side effects by the time on the drug, gender and age of the people who have side effects while taking Plaquenil. The review is based on 57,733 people who have side effects while taking the drug from Food and Drug Administration FDA. The information that eHealthMe analyzes includes Check with your doctor immediately if any of the following side effects occur Incidence not known. Blistering, peeling, loosening of the skin blurred vision or other vision changes chest discomfort, pain, or tightness cough or hoarseness dark urine decreased urination defective color vision diarrhea difficulty breathing The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Plaquenil 200 mg tablets side effects Plaquenil - Side Effects, Uses, Dosage, Overdose., Hydroxychloroquine Oral Route Side Effects - Mayo Clinic Long-term effects of taking plaquenilIs chloroquine sulfonamides Hydroxychloroquine side effects may vary greatly from very mild side effects that go away with time to severe side effects like eye damage, ear damage, or heart problems. Some side effects may be experienced as the body adjusts to hydroxychloroquine but may diminish as the body becomes used to the drug. Hydroxychloroquine Plaquenil Success, Reviews and Side.. Hydroxychloroquine Plaquenil. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg administration. Inactive Ingredients Dibasic calcium phosphate USP, hypromellose USP, magnesium stearate NF, polyethylene glycol 400 NF, polysorbate 80 NF, corn starch, titanium dioxide USP, Hydroxychloroquine side effects. Hydroxychloroquine side effects may vary greatly from very mild side effects that go away with time to severe side effects like eye damage, ear damage, or heart problems. Some side effects may be experienced as the body adjusts to hydroxychloroquine but may diminish as the body becomes used to the drug. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia.