Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil toxicity symptoms liver Ic hydroxychloroquine Chloroquin and ferroquine structure Chloroquine er derived vaculation Other side effects people have besides Optic neuropathy * Vision Blurred 1 person, 25.00%. Rash Erythematous redness of the skin 1 person, 25.00%. Papilloedema optic disc swelling 1 person, 25.00%. Oropharyngeal Pain 1 person, 25.00%. Halo Vision rainbow vision 1 person, 25.00%. Side Effects extreme dry eyes, seeing flashing lights, fatigue, possible weight gain I have been taking this about 1 month for peripheral neuropathy and Sjorgren's syndrome. My dry eye pr. My dry eye pr. Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil side effects neuropathy Hydroxychloroquine Side Effects, Dosage, Uses, and More, Hydroxychloroquine Sulfate Neuropathy Peripheral Reports. Plaquenil maculopathy oct imagesChloroquine phosphate aquariumPlaquenil opinieCan plaquenil worsen neuropathyPlaquenil drug test Aug 14, 2017 Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Hydroxychloroquine Side Effects -. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Plaquenil and small fiber neuropathy I used Plaquenil years ago for extreme muscle and joint issues and it seemed to work fine. All my issues were resolved over a years time on low doses. I have been on the plaquenil 200 mgm for about 4 months now. I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Noticed nothing different. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. eHealthMe has been monitoring drugs since 2008. Our original studies have been referenced on 600+ peer-reviewed medical publications. On eHealthMe, patients can.