My worst symptoms so far have been raynauds, fatigue, telangiectasias , heart burn, and digital ulcers. I'm fortunate that my lungs have been unaffected up to this point but I'm worried that contracting the virus could cause fibrosis in the lungs and lead to ILD and PAH. Plaquenil uptodate Plaquenil leaky gut CREST Syndrome is a form of scleroderma that is characterized by least two of the following symptoms calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, telangiectasia. Common symptoms reported by people with CREST syndrome Sjögren syndrome SjS, SS is a long-term autoimmune disease that affects the body's moisture-producing glands. Primary symptoms are a dry mouth and dry eyes. Other symptoms can include dry skin, vaginal dryness, a chronic cough, numbness in the arms and legs, feeling tired, muscle and joint pains, and thyroid problems. Sjogren's SHOW-grins syndrome is a disorder of your immune system identified by its two most common symptoms — dry eyes and a dry mouth. The condition often accompanies other immune system disorders, such as rheumatoid arthritis and lupus. Anybody have any knowledge about this that they can share? I've been trying to do some research but haven't come up with any solid answers. Plaquenil crest syndrome Scleroderma Life Expectancy Johns Hopkins Arthritis Center Ask The., Sjögren syndrome - Wikipedia Plaquenil tabletsChloroquine resistant p falciparumHydroxychloroquine retinal According to my opinion, Raynaud's phenomenon is a part of CREST syndrome of systemic sclerosis. In case that is troubling you, the best treatment that I have found very successful is the use of crushed Sorbitrate tablets in coconut oil and apply them to massage over th. Common "Crest Syndrome" queries answered by top doctors iCliniq. Sjogren's syndrome - Symptoms and causes - Mayo Clinic. How effective is Plaquenil for Systemic sclerosis.. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Undifferentiated connective tissue disease UCTD is an autoimmune disease that can affect several systems in the body. Connective tissue disease CTD is classified as undifferentiated CTD when signs and symptoms are consistent with a CTD, but do not fulfill the diagnostic or classification criteria for one of the previously defined CTDs for example, rheumatoid arthritis or lupus. CREST syndrome, also known as the limited cutaneous form of systemic sclerosis lcSSc, is a multisystem connective tissue acronym "CREST" refers to the five main features calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.