One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Chloroquine mechanism malaria Plaquenil helps.me.sleep Hydroxychloroquine weight based dosing Saltwater fish chloroquine compatible with acriflavine With the use of hydroxychloroquine in treatment of autoimmune dermatoses, we typically recommend annual eye examinations owing to the risk of hydroxychloroquine retinopathy, which has a 7.5% prevalence in patients treated for more than 5 years. 6 Given the comparable rate of ocular complications in patients with AD receiving dupilumab, we should consider recommendation for routine eye examinations in our dupilumab medication counseling. We are grateful to have a highly effective medication. Ocular toxicity ranged from non-significant keratopathy to a potentially blinding retinopathy as described previously with varying doses of HCQ. 1, 2 In 2016 the American Academy of Ophthalmology. Hydroxychloroquine HCQ retinopathy can result in permanent vision loss. In early stages of HCQ retinopathy, patients are usually asymptomatic with preservation of visual acuity. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Downes sm hydroxychloroquine retinopathy Taking Plaquenil for Rheumatoid Arthritis, Hydroxychloroquine and the eye an old unsolved problem Eye Plaquenil rheumatoid arthritis remission PurposeThe aim of this case series is to raise awareness of the emerging issue of serious retinal damage caused by the prolonged use of hydroxychloroquine HCQ and the importance of adequate and appropriate monitoring of visual function during treatment. Patient and methodsThis is a small retrospective case series of 3 patients on long-term HCQ who developed serious symptomatic retinal toxicity confirmed on imaging and functional testing. ResultsAll 3 patients were treated with HCQ for over. Hydroxychloroquine retinopathy an emerging problem.. Hydroxychloroquine retinopathy A review of imaging. Hydroxychloroquine retinopathy Eye. Spectral domain optical coherence tomography as an effective screening test for hydroxychloroquine retinopathy the 'flying saucer' sign. Downes SM. Hydroxychloroquine retinopathy. Eye 2017. When the clinician that detects early retinopathy does not discontinue CQ/HCQ therapy, the prognosis is a progressive loss of paracentral vision followed by loss of central vision and night blindness. Even when the clinician discontinues therapy, retinopathy can progress for many years. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative.