Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Chloroquine lysosomal membrane permeabilization Effects of long term use of plaquenil Can plaquenil cause hearing loss Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat. Nov 25, 2019 Detailed Hydroxychloroquine dosage information for adults and children. Includes dosages for Rheumatoid Arthritis, Systemic Lupus Erythematosus, Malaria Prophylaxis and more; plus renal, liver and dialysis adjustments. Chloroquine phosphate is used occasionally to decrease the symptoms of rheumatoid arthritis and to treat systemic and discoid lupus erythematosus, scleroderma, pemphigus, lichen planus, polymyositis, sarcoidosis, and porphyria cutanea tarda. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine cutaneous lupus Chloroquine DermNet NZ, Hydroxychloroquine Dosage Guide with Precautions - Compare hydroxychloroquine prices The antimalarial agents chloroquine CQ and hydroxychloroquine HCQ are considered to be effective for the treatment of cutaneous lupus erythematosus CLE and the symptoms associated with systemic lupus erythematosus SLE such as rashes, joint pain, and fatigue. Effects of Hydroxychloroquine in Patients With Cutaneous.. Chloroquine MedlinePlus Drug Information. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Cutaneous Lupus Erythematosus. Lupus is an autoimmune disease, which affects multiple organs and systems in the body. An individual's own immune system attacks various cells causing a wide variety of signs and symptoms. With regards to the skin, there are lupus-specific skin lesions and non-specific skin lesions. Hydroxychloroquine and chloroquine phosphate have shown beneficial effects in treating discoid lupus erythematosus DLE. Additionally, The antimalarial drugs may prevent the development of systemic lupus erythematosus SLE in patients with DLE, and they might decrease the risk of cardiovascular disease. Alternative therapies, anecdotal reports, and small, open-label trials as reported by. Background. Hydroxychloroquine is widely used for the treatment of cutaneous lupus erythematosus CLE. Although new recommendations exist for hydroxychloroquine dosing, there is still uncertainty about the dosage that will elicit a satisfactory response in CLE while limiting adverse effects, specifically retinopathy.