Chloroquine phosphate drug study

Discussion in 'Canadian Pharmacies Online' started by evgeny64, 29-Feb-2020.

  1. mjuler Moderator

    Chloroquine phosphate drug study


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

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    The study is a double-blind, randomised, placebo-controlled trial that will be conducted in health care settings. After obtaining fully informed consent, the investigator will recruit healthcare workers, or other individuals at significant risk who can be followed reliably for 5 months. 10,000. A recent study abstract published in PubMed Journal stated the efficacy of chloroquine phosphate as a potential treatment for the current spread of COVID-19. The study outlined that in clinical trials in China, chloroquine, an FDA-approved drug for the treatment of malaria, was effective and safe in dealing with COVID-19 associated pneumonia in a lab dish. The study outlined that in clinical trials in China, chloroquine, an FDA-approved drug for the treatment of malaria, was effective and safe in dealing with COVID-19 associated pneumonia in a lab dish. This triggered a spread of anticipation throughout the world about a possible treatment for the pandemic virus.

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Chloroquine phosphate drug study

    Breakthrough Chloroquine phosphate has shown apparent., Malaria Drug Shows Promise as Coronavirus Treatment.

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  7. Chloroquine, a medication used to prevent and to treat malaria, has just been confirmed as one of the three anti-viral drug for Coronavirus. The search for the cure of Coronavirus has been on for some time

    • Chloroquine confirmed as anti-viral drug for Coronavirus.
    • Malaria Drug Shows Promise as Coronavirus Treatment.
    • Chloroquine Phosphate chloroquine phosphate dose, indications..

    Chloroquine is a cheap and safe drug that has been used for more than 70 years. It is used to prevent and treat malaria and is efficacious as an anti-inflammatory agent for the treatment of rheumatoid arthritis and lupus erythematosus. Chloroquine data from Covid-19 trials Data from the drug’s studies showed ‘certain curative effect’ with ‘fairly good efficacy’. According to Sun, patients treated with chloroquine demonstrated a better drop in fever, improvement of lung CT images, and required a shorter time to recover compared to parallel groups. Chloroquine phosphate, an antimalarial drug, is shown to have yielded positive data against COVID-19 associated pneumonia in multicenter clinical trials conducted in China. It is slated to be included in the next version of the Guidelines for the Prevention, Diagnosis, and Treatment of Pneumonia Caused by COVID-19 issued by the National Health.

     
  8. bad1 New Member

    Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. Is Hydroxychloroquine Plaquenil an Immunosuppressant. Hydroxychloroquine - an overview ScienceDirect Topics Immunosuppressants The Myositis Association
     
  9. fotoagent Well-Known Member

    Quinine was frequently prescribed as an off-label treatment for leg cramps at night, but this has become less common due to a warning from the US Food and Drug Administration (FDA) that this practice is associated with life-threatening side effects. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Quinine - Wikipedia Hydroxychloroquine - Side Effects, Dosage, Interactions.
     
  10. gunshot Guest

    Sjogren's Syndrome Symptoms, Causes, Diagnosis, Treatment WebMD explains the causes, symptoms, and treatment of Sjogren's syndrome, a condition in which your eyes, mouth, and other parts of your body get dried out.

    Sjogren's syndrome - Symptoms and causes - Mayo Clinic
     
  11. Beygul Well-Known Member

    Plaquenil Hydroxychloroquine - Side Effects, Dosage. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as.

    Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis