It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. What was hydroxychloroquine originally used for Plaquenil immunosuppressive therapy Phototoxic reaction to plaquenil Like the others have said it's best not to take meds prescribed for reflux, such as Omeprazole or Lanzoprazole, at the same time as Plaquenil as they can make it less effective. I need to leave at least a couple of hours between my morning Lanzoprazole and my first dose of Plaquenil otherwise I feel sick. Except today I started having some heartburn after taking it. It says on the bottle I can’t take an antacid for at least four hours after taking the Plaquenil. Has anyone else experienced heartburn while taking Plaquenil and if so what did you do to avoid or ease the heartburn? Btw I always make sure to take it with a meal. However, some drugs can interact with hydroxychloroquine. Indigestion remedies for example, antacids including some over-the-counter preparations can stop hydroxychloroquine being absorbed. It's recommended you wait at least four hours after taking hydroxychloroquine before you take an indigestion remedy. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Can you take omeprazole with plaquenil Can I take other medicines with omeprazole? - Netdoctor, Plaquenil and heartburn rheumatoid Chloroquine sensitivePlaquenil stomach achePlaquenil effect on sperm Omeprazole Prilosec, esomeprazole Nexium, and pantoprazole Protonix belong to a class of medications known as proton pump inhibitors that can interfere with how you absorb your thyroid medications. If you take these medications at the same time, your provider may need to increase the dosage of your thyroid medication to compensate. Things That Can Mess With Your Thyroid Medication - GoodRx. Hydroxychloroquine Side-effects, uses, time to work. Protecting your eyesight when taking Plaquenil Lupus.. Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in. I take omeprazole Prilosec, a proton pump inhibitor, to reduce stomach acid. Are there supplements I should avoid, or be taking, due to this drug? Answer Omeprazole Prilosec, Nexium, and other proton pump inhibitor drugs can be affected by taking supplements, and can affect your ability to absorb certain vitamins and minerals. St. Omeprazole oral capsule can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works.