In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Plaquenil side effects back pain Treatment of discoid lupus erythematosus with chloroquine Take this drug at the times recommended by your doctor. If you take this drug at times other than the ones prescribed, the level of the drug in your body could increase or decrease. If it increases, you could have more side effects. If it decreases, the drug might lose its effectiveness. Once you have been taking the medication for a while and your condition has improved, your doctor may instruct you to lower your dose until you find the dose that works best with the fewest side. In a small percentage of patients, side effects may require temporary reduction of the initial dosage. Maintenance adult dosage When a good response is obtained, the dosage may be reduced by 50 percent and continued at a maintenance level of 200 mg to 400 mg 155 to 310 mg base daily, administered as a single daily dose or in two divided doses. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. What if you take double the dosage of plaquenil Plaquenil Tablets - Medsafe, Plaquenil Oral Uses, Side Effects, Interactions. Mechanism of action of hydroxychloroquine in fibromyalgia The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight. One kilogram kg equals 2.2 pounds. Women with lupus who are OVER their ideal body weight should go by these dosing rules Protecting your eyesight when taking Plaquenil Lupus.. Plaquenil Dosage Guide -. Plaquenil Side Effects on Your Eyes and Vision. If you are being given Plaquenil for rheumatoid arthritis, SLE or DLE, do not take a double dose to make up for the dose missed. Just continue with the appropriate dose on the next day. If you are being given Plaquenil for suppression or treatment of malaria, you should take your tablets as soon as you remember, and go back to taking it as you. Take Plaquenil with a meal or a glass of milk. To prevent malaria Start taking Plaquenil 2 weeks before entering an area where malaria is common. Continue taking the medicine regularly during your stay and for at least 8 weeks after you leave the area. To treat malaria Plaquenil is usually given for 3 days. Before you begin taking any medication, you should have an open and honest conversation with your doctor about all aspects of your lupus if you haven’t already. Long-term use of Plaquenil is associated with damage to the retina in the eye, the portion of the eyeball that is sensitive to light.