It may be effective in a variety of upper and lower respiratory tract infections, kidney and urinary tract infections, gastrointestinal tract infections, skin and wound infections, sepsis, and other infections caused by sensitive organisms. Co-trimoxazole decreases the risk of recurrence of retinochoroiditis. Is plaquenil a thiopurine drug Plaquenil and eyesight Recently, several studies have emphasized that chloroquine CQ resistance CQR can be quantified in two very distinct ways, depending on whether sensitivity to the growth inhibitory effects or parasite-kill effects of the drug are being measured. Class pcn combo, cell wall abx. Target peptidoglycan synthetic enzymes, D-ala, D-ala transpeptidase -- avoid degradation of β-lactam ring. Resistance target modification, avoid some inactivation by plasmid β-lactamase, NOT chromosomal. Spectrum Staph aureus, E. coli, H. flu -- NOT enterobacter or pseudomonas. Table 2 Tuberculous Meningitis Diagnosis and Treatment Overview Ebstein's anomaly), urinary tract defects, oral clefts, and club foot in epidemiological studies. Its use during the first trimester (during organogenesis) and 12 weeks prior to pregnancy has been associated with an increased risk of congenital malformations, especially malformations associated with maternal folic acid deficiency (which is most likely related to the mechanism of action of co-trimoxazole) such as neural tube defects such as spina bifida, cardiovascular malformations (e.g. Is hyd chloroquine static or cidal Fast in vitro methods to determine the speed. - SpringerLink, Antibiotics Flashcards - Quizlet Chloroquine during pregnancyHydroxychloroquine malariaWhere is chloroquine resistant malaria Levaquin levofloxacin is a fluoroquinolone flor-o-KWIN-o-lone antibiotic that fights bacteria in the body. Levaquin is used to treat different types of bacterial infections. Levofloxacin is also used to treat people who have been exposed to anthrax or certain types of plague. Fluoroquinolone antibiotics can cause serious or disabling side effects. Levaquin Uses, Dosage & Side Effects -. Table 2 Tuberculous Meningitis Diagnosis and Treatment.. Development of a rapid and reliable assay for in vitro.. Medical uses. Co-trimoxazole was claimed to be more effective than either of its components individually in treating bacterial infections, although this was later disputed. Cidal/Static-Cidal Special-avoid alcohol ingestion; may cause metallic taste and furring of the tongue; Similar drug is Tinidazole; may get nausea due to increased penetration CNS based, not gut irritation Glucose is an essential nutrient for Plasmodium falciparum and robust glycolytic activity is indicative of viable parasites. Using NMR spectroscopy, we show that P. falciparum infected erythrocytes consume ~20 times more glucose, and trophozoites metabolize ~6 times more glucose than ring stage parasites.