It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Chloroquine resistant malaria treatment Chloroquine toxicity treatment Plaquenil muscle pain Hydroxychloroquine qt prolongation I think this rash is just starting, so I don't know if it will develope into hives or what. Could this be related to the plaquenil. I have had some weird hive like rashes in the past that I was not able to get biopsied for lupus, so I don't know if this could be the case or not. Sep 13, 2019 Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Hydroxychloroquine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away headache; dizziness; loss of appetite; nausea; diarrhea; stomach pain; vomiting; skin rash; If you experience any of the following symptoms, call your doctor immediately This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Rash caused by plaquenil Hydroxychloroquine Side Effects, Dosage, Uses, and More, Plaquenil Side Effects Common, Severe, Long Term - Plaquenil perte cheveux A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling especially of the face/tongue/throat, dizziness, trouble breathing. This is not a complete list of possible side effects. Plaquenil Oral Uses, Side Effects, Interactions, Pictures, Warnings.. Hydroxychloroquine MedlinePlus Drug Information. Allergic reaction to Plaquenil Lupus Forums at The Lupus Site. Less common side effects Skin rashes or changes in skin color. Thinning hair. Weakness. Irregular heartbeat. Mental/mood changes. Arm/leg/back pain. Anxiety. Depression. Ringing in the ears or hearing loss. Worsening of skin conditions If you have psoriasis, Plaquenil may make your. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is.