I've had referrals to cardiology and neurology, as well as my usual rheumy and respirologist. Meanwhile, I have continued to be convinced that the explanation lies in the meds that I have been taking. They have controlled my primary AI problems very well, but these newer symptoms have persisted. Hydroxychloroquine dosing Btk calcium chloroquine Chloroquine phosphate and pregnancy Lupus can cause serious renal damage up to complete loss of kidney function. HCQ is a background therapy in lupus management. 1 HCQ can affect glucose homeostasis and may lead to serious hypoglycaemia episodes in both diabetic and non-diabetic population. The optimal HCQ dosing in patients on dialysis is still open to debate. The beneficial changes in glucose metabolism and insulin sensitivity reported among patients with lupus, patients with type 2 diabetes, and in animal models suggest that these effects are not specific to rheumatoid arthritis. 8-13 The fact that antimalarials favorably affect dyslipidemia in patients with rheumatoid arthritis and lupus, independent of steroid use, 32 suggests the possibility that hydroxychloroquine may have a role in reducing 2 key risk factors for atherosclerosis, namely. PLAQUENIL has been shown to cause severe hypoglycemia including loss of consciousness that could be life threatening in patients treated with or without antidiabetic medications see DRUG INTERACTIONS and ADVERSE REACTIONS. Patients treated with PLAQUENIL should be warned about the risk of hypoglycemia and the associated clinical signs and symptoms. Last night, I was having a particularly brutal time, with recurrent episodes, when it occurred to me that my symptoms were very akin to those of hypoglycaemia. My rheumy thinks it is Fibromyalgia and prescribed gabapentin to improve sleep quality. Hypoglycemia plaquenil Plaquenil and hypoglycemia? rheumatoid, Hydroxychloroquine and Risk of Diabetes in Patients With. Hydroxychloroquine side effects retinopathy Plaquenil makes me feel like my stomach is turning inside out and I swear I can feel it heating up the blood in my veins. I felt hypoglycemic when I took it without food or with just light carbs. Take care and be sure to inform your doctor of what occurred. Plaquenil and Low Blood Sugar - Inspire. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Plaquenil Side Effects Common, Severe, Long Term -. So back to the Sjogren's World Forums participant this person noticed that after beginning to take Plaquenil, it became more difficult to keep her diabetes in control occasionally her blood sugar became too low and she had symptoms of hypoglycemia feeling very anxious, tremor, feeling suddenly very hungry, perspiring heavily, and feeling faint. Several others chimed in, many of whom were not diabetic, and said that they noticed the same thing. Adults. 200 mg 155 mg base to 400 mg 310 mg base PO per day, administered as a single dose or in 2 divided doses. Antimalarials and/or glucocorticoids are of benefit and may be used for the treatment of SLE without major organ manifestations; however, judicious use of hydroxychloroquine is recommended. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Hydroxychloroquine Plaquenil is used to treat.