Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Hydroxychloroquine for lupus user reviews Lung nodules plaquenil Children—Use and dose must be determined by your doctor. For treatment of lupus Adults—200 to 400 milligrams mg taken as a single dose or in two divided doses once a day. However, dose is usually not more than 400 mg once a day. Children—Use and dose must be determined by your doctor. Missed Dose Plaquenil comes in 200 mg tablets, and many doctors just off-handedly put everyone on 200 mg twice a day. By the old standards, obese people, if dosed by their actual weight, could be overmedicated, Dr. Marmor said. If you’re short, the standard prescription of 200 mg of Plaquenil, twice daily, is too much, he said. The recommended dosage is no more than 6.5 mg/kg/day, using the standard known as “ideal weight,” which factors in height. Dr. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Plaquenil standard dose Hydroxychloroquine Uses, Dosage & Side Effects -, Despite Plaquenil dosing recommendations, retinal toxicity. Hydroxychloroquine-mediated retinopathyChloroquine &Hydroxychloroquine sulfate for skinUniquin hydroxychloroquine Dosage Hydroxychloroquine Plaquenil® is the drug of choice among antimalarials. Chloroquine is not commonly used because of greater toxicity on the eye. The usual dose of Plaquenil is 400mg/day but 600mg/day is sometimes used as part of an induction regimen. It may be prescribed as a single daily dose or in divided doses twice per day. Rheumatoid Arthritis Treatment Options Johns Hopkins.. Rx Side Effects New Plaquenil Guidelines and More.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Maintenance adult dosage When a good response is obtained, the dosage may be reduced by 50 percent and continued at a maintenance level of 200 mg to 400 mg 155 to 310 mg base daily, administered as a single daily dose or in two divided doses. SAN FRANCISCO – Hydroxychloroquine Plaquenil dosing based on actual body weight – instead of ideal weight – is appropriate for patients with systemic lupus erythematosus SLE, according to a review of 686 lupus patients at Johns Hopkins University in Baltimore. Most were dosed by actual weight, 6.5 mg/kg up to a maximum of 400 mg/day. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools.