PLAQUENIL film-coated tablets cannot be divided, therefore they should not be used to treat patients who weigh less than 31 kg. For radical cure of The recommended adult dosage is 200 to 400 mg (155 to 310 mg base) daily, administered as a single daily dose or in two divided doses. The incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded. Plaquenil can& 39 Eye pain plaquenil Mylan hydroxychloroquine In a small percentage of patients, side effects may require temporary reduction of the initial dosage. Maintenance adult dosage When a good response is obtained, the dosage may be reduced by 50 percent and continued at a maintenance level of 200 mg to 400 mg 155 to 310 mg base daily, administered as a single daily dose or in two divided doses. New research underscores the protective benefits of the medication hydroxychloroquine Plaquenil. The study compared clinical and laboratory information of more than 500 people with lupus and found that people who discontinued the treatment after less than one year were more likely to experience flares compared to those who took the drug for more than a year. Systemic Lupus Erythematosus Living With Lupus Donald Thomas, MD, FACP, FACR Author of “The Lupus Encyclopedia A Comprehensive Guide for Patients and Families In a small percentage of patients, side effects may require temporary reduction of the initial dosage. 400 mg to 600 mg (310 to 465 mg base) daily, administered as a single daily dose or in two divided doses. Plaquenil and discoid lupus s dosage Compare Current Discoid Lupus Erythematosus Drugs and., Longer-Term Use of Plaquenil Protects Against Lupus Flares Lupus. Hydroxychloroquine side effects weight lossPlaquenil and radiation Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Systemic Lupus Erythematosus Living With Lupus. Effects of Hydroxychloroquine in Patients With Cutaneous Lupus.. Regarding hydroxychloroquine levels and lupus activity, Costedoat- Chalumeau et al measured whole blood levels in 143 individuals taking a standard dose of 400 mg per day and found a lower hydroxychloroquine level in those with active disease and that lower baseline levels were predictive of disease flare. In 1956, the U. S. Food and Drug Administration approved HCQ for symptoms of lupus and rheumatoid arthritis, particularly skin inflammation, hair loss, mouth sores, fatigue, and joint pain. Dosing. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye.