Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Lariago chloroquine phosphate 250 mg Hydroxychloroquine narcotic Chloroquine malaria chemical formula Potential adverse effect with hydroxychloroquine Aug 29, 2014 One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. I had a skin rash from plaquenil hydroxychloroquine. I was put on a 21 day taper of prednisone. How long befor more I had a skin rash from plaquenil hydroxychloroquine. I was put on a 21 day taper of prednisone. How long before the prednisone increases my odds of catching viruses? I'm on plaquenil alone, I'm trying to hold the line and put off methotrexate as long as possible. The Plaquenil is supposed to kick in in 3 to 6 months. I think it was 8 months for me. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. How long before plaquenil works Hydroxychloroquine Side-effects, uses, time to work, How long does it take for plaquenil hydroxychloroquine to. Chloroquine nhibts clathrin mediated endocytosisHydroxychloroquine in lupus pregnancyIs a side effect of hydroxychloroquine making my cheeks flushPlaquenil e depressionePlaquenil toxicity macular oct Plaquenil takes quite a long time to get to its peak effectiveness depending on what you read, anywhere from 3 months to a year. Unless you are having significant side effects, try to give it at least 6 months before you decide it doesn't work for you. PLAQUENIL" Rheumatoid Arthritis Community - Support Group. How long did Plaquenil/Hydroxychloroquine take? DailyStrength. Plaquenil - How long to take effect?. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Most people who take Plaquenil also take other medicines for pain and stiffness. How does Plaquenil work? Plaquenil changes the way your immune system works. I know I've asked this question before, but with so many new people and so much time that's passed, I thought I'd ask again. How long did it take for Plaquenil to become effective for you? Meaning, when did you start to feel some relief from your lupus symptoms after you started taking.