Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Method of action of chloroquine Hydroxychloroquine and chloroquine comparison 10-2 plaquenil Treating ra with plaquenil Most rheumatologists recommend patients undergo a baseline eye examination prior to starting Plaquenil and be re-examined in the future depending on their risk for developing the condition. Risk factors include advanced age and having pre-existing retinal disease. Current testing for Plaquenil toxicity may include Visual field testing to evaluate for missing spots near the center of the vision. Color photographs of the macula. Fluorescein angiography FA. Optical coherence tomography OCT. Fundus autofluorescence. Multifocal electroretinograms mf. Plaquenil and Your Eyes Here is an eye test that is easy for all of us to do online, without going to the doctor right away. Scroll down after you go to this site until a graph shows up with a dot in the center. Look at the dot with one eye at a time, and if the lines change, then you might need to see the doctor. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Eye screening for plaquenil How to Succeed in Plaquenil Screenings, Plaquenil Toxicity Screening - Retina Group of New York Side effects of stopping hydroxychloroquineMedicine used for malaria hydroxychloroquineHow to stop chloroquine itching Hydroxychloroquine Screening You have been invited to attend a Hydroxychloroquine Screening appointment at the Eye Treatment centre at the West Suffolk Hospital. Hydroxychloroquine screening. Eye exam / Plaquenil -. Hydroxychloroquine toxicity - EyeWiki. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. It is now considered for new disease applications in diabetes, heart disease and adjunct cancer therapies 2. Macular Society Eye screening for patients taking hydroxychloroquine Hydroxychloroquine is a medication used to treat several conditions including rheumatoid arthritis, systemic lupus erythematosus, some skin conditions especially photosensitive ones and others that involve inflammation. It was previously used in the treatment and At a screening for retinal toxicity due to Plaquenil intake, the ophthalmologist will do a complete eye exam including dilation of the pupils to look at the inner layers of the eye. Images of the.