Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil as it affects the eyes symptoms Chloroquine pronounce How often do you take plaquenil Do not take more or less of it or take it more often than prescribed by your doctor. If you are taking hydroxychloroquine for symptoms of rheumatoid arthritis, your symptoms should improve within 6 months. If your rheumatoid arthritis symptoms do not improve, or if they worsen, stop taking the drug and call your doctor. Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. PLAQUENIL may prevent life-threatening complications. PLAQUENIL prolongs the QT interval. Ventricular arrhythmias and torsades de pointes have been reported in patients taking PLAQUENIL see OVERDOSAGE. Therefore, PLAQUENIL should not be administered with other drugs that have the potential to prolong the QT interval see DRUG INTERACTIONS. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Why plaquenil should not be cut in half Plaquenil Hydroxychloroquine Side effects, Images, Uses., Lupus Medicines Hydroxychloroquine - Brigham and Women's Hospital Is hydroxychloroquine antiviralHydroxychloroquine pneumococcal vaccine Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. Taking Plaquenil for Rheumatoid Arthritis. PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION. Cutting Pills in Half Could Pose Problems. Based upon what you both report, it sounds like you should have if you can notice something within days of changing just a portion of the dose. Good luck today. I'd be interested in hearing what he says, since Plaquenil is not known for effecting the heart, etc like you report. Which is mostly why I am taking it also so I have my fingers crossed there. I just started and I am cutting my 200tmg pill in half and only taking the 1/2 for a couple of weeks per my rheumys recommendation as it causes stomach upset at first. I would say try it again but only start with 100mg, not the whole 400, I have been on plaquenil for 8 months and have lost 60 pounds from it this is a good thing also the fatigue is completely gone as is the morning stiffness. Plaq did not do enough to end my flare and get me off pred so doc convinced me to add MTX. She tried to take me off the plaq at my last appointment and I would NOT let her.